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Quickmice™ Yara KI Asin isọdi

quickmice-fast-ki-mouse-isọdi-ọja

Knock-in (Kọ-in, KI) jẹ ilana kan ti o nlo isọdọkan isokan ti awọn Jiini lati gbe jiini iṣẹ ṣiṣe exogenous kan si ọna isokan ninu sẹẹli ati jiini, ati gba ikosile daradara ninu sẹẹli lẹhin isọdọtun pupọ.

Yoo gba oṣu 5-6 lati gba awọn eku heterozygous Neo ti paarẹ ati apapọ awọn oṣu 10-12 lati kọ awọn awoṣe asin homozygous KI kan pẹlu awọn oṣuwọn aṣeyọri kekere nipa lilo awọn ilana ibile, nitori awọn imuposi wọnyi ni iṣesi chimera kekere ati nilo ibarasun pẹlu Asin si gba awọn eku heterozygous Neo-piparẹ, ati lẹhinna ibisi awọn eku heterozygous ti a bi fun awọn iran 2-3 lati gba awọn eku homozygous KI.

Iran tuntun ti Imọ-ẹrọ Igbaradi Asin Dekun

TurboMice™

A le pese fun ọ ni kiakia pẹlu awọn awoṣe asin homozygous KI nipa lilo imọ-ẹrọ TurboMice ™ lati mu iwọn aṣeyọri pọ si.

Da lori eto ṣiṣatunṣe jiini ti o dara julọ nipasẹ awọn onimọ-jinlẹ wa, a le pari ibojuwo ti awọn sẹẹli sẹẹli ọmọ inu oyun ti a ṣatunkọ laarin awọn ọjọ 3-5, lẹhinna kọ oyun tetraploid.Lẹhin iṣẹ abẹ iya, awọn eku homozygous humanized le ṣee gba laarin awọn oṣu 2-4, eyiti o le fipamọ awọn oṣu 7-8 fun awọn alabara.

Akoonu Iṣẹ

Iṣẹ No. Awọn atọka imọ-ẹrọ akoonu ifijiṣẹ Yiyika ifijiṣẹ
MC002-1 gigun ti jiini kan <5kb 3-9 KI homozygous akọ eku 2-4 osu
MC002-2 gigun ti jiini kan <5kb 10-19 KI homozygous akọ eku 2-4 osu
MC002-3 gigun ti jiini kan <5kb 20 KI homozygous akọ eku 3-5 osu
MC002-4 ipari ti Jiini ẹyọkan jẹ 5kb-10kb 3-9 KI homozygous akọ eku 3-4 osu
MC002-5 ipari ti Jiini ẹyọkan jẹ 5kb-10kb 10-19 KI homozygous akọ eku 3-4 osu
MC002-6 ipari ti Jiini ẹyọkan jẹ 5kb-10kb 20 KI homozygous akọ eku 3-5 osu

Pe wa

Jọwọ kan si wa ni:

1) Jọwọ ṣe igbasilẹ ati fọwọsi fọọmu ni isalẹ.Fọọmu Ibere ​​Quotation》, ati firanṣẹ nipasẹ imeeli siMingCelerOversea@mingceler.com;

2) Te: +86 181 3873 9432;

3) LinkedIn: https://www.linkedin.com/company/mingceler/

Fọọmu Ibere ​​Quotation.docx

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